Volume 25, Issue 3 (In Press_ Autumn 2021)                   2021, 25(3): 0-0 | Back to browse issues page

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Abdollahi F, Keshavarz rad M, Mirzapour M, Rajabi Yekta M, Alimohammadiha A, Nouri M et al . Mortality Risk Factors among Hospitalized older Patients with COVID-19. Journal of Inflammatory Diseases. 2021; 25 (3)
URL: http://journal.qums.ac.ir/article-1-3265-en.html
1- Department of Medical Sciences, Qazvin branch, Islamic Azad University, Qazvin, Iran.
2- Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
3- Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran
4- Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran. , ammotalebi@yahoo.com
Abstract:   (647 Views)
Background: COVID-19 is an infectious disease with a high mortality rate among older people. Therefore, the present study attempted to investigate the death rate and related factors among hospitalized older patients with COVID-19 in Qazvin, Iran.
Methods: A total of 430 randomly selected older patients with COVID-19 admitted to two university hospitals were included in this descriptive and cross-sectional study. Older patients’ information was extracted from the electronic health records. Independent t-test, chi-square, and multivariate logistic regression model were used for the data analysis.
Results: Mean (SD) age for older patients was 72.83 (8.81) years. Hypertension (n=234, 54.4%), diabetes mellitus (n=148, 34.4%), and cardiovascular disorders (n=127, 29.4%) were the most prevalent comorbidities. Dyspnea (n=300, 69.8%), cough (n=232, 54.0%), fever (n=186, 43.3%), and general malaise (n=168, 39.1%) were the most frequent clinical symptoms. There was in-hospital mortality in 108 (25.1%) older patients. Multivariate regression demonstrated rising odds of in-hospital death related with age (odds ratio (OR) = 1.037, CI=1.007 - 1.068), WBC count (OR=1.187, CI=1.114 - 1.264), hemoglobin (OR=0.812, CI=0.720 - 0.914), platelet (OR=0.993, CI=0.989 - 0.996), and oxygen saturation (OR=0.950, CI=0.967 - 0.932) on admission.
Conclusions: Based on the findings of this study, older age, WBC count, hemoglobin, oxygen saturation, and platelet count were found to be predictive of death among older patients with COVID-19. Identification of these risk factors would assist the care provider for timely intervention in the prevention of death.
Article number: 2
     
Type of Study: Research | Subject: Infectious Disease

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