Volume 25, Issue 3 (Autumn 2021)                   2021, 25(3): 145-152 | Back to browse issues page

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Abdollahi F, Keshavarz Rad M, Mirzapour M, Rajabi Yekta M, Alimohammadiha A, Nouri M et al . Mortality Risk Factors Among Hospitalized Older Patients With COVID-19. Journal of Inflammatory Diseases. 2021; 25 (3) :145-152
URL: http://journal.qums.ac.ir/article-1-3265-en.html
1- Department of Medical Sciences, Qazvin Branch, Islamic Azad University, Qazvin, Iran.
2- Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.
3- Social Determinants of Health Research Center, Research Institute for Prevention of Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran. , ammotalebi@yahoo.com
Abstract:   (15063 Views)
Background: The Coronavirus disease 2019 (COVID-19) is an infectious disease with a high mortality rate among older people.
Objective: The current study aims to investigate the death rate and related factors among hospitalized older patients with COVID-19 in Qazvin, Iran.
Methods: In this descriptive and cross-sectional study, 430 older inpatients with COVID-19 (Mean±SD age: 72.83±8.81) admitted to two hospitals in Qazvin, Iran were randomly selected. Their information was extracted from their electronic health records. Independent t-test, chi-square test, and multivariate logistic regression analysis were used for the data analysis.
Findings: Hypertension (n=234, 54.4%), diabetes mellitus (n=148, 34.4%), and cardiovascular diseases (n=127, 29.4%) were the most prevalent comorbidities. Dyspnea (n=300, 69.8%), cough (n=232, 54.0%), fever (n=186, 43.3%), and general malaise (n=168, 39.1%) were the most frequent clinical symptoms. There was in-hospital mortality in 108 (25.1%) older inpatients. Multivariate regression results showed that the risk of in-hospital death was significantly related to the inpatients’ age (OR=1.037, 95%CI=1.007-1.068), white blood cell count (OR=1.187, 95%CI=1.114-1.264), hemoglobin level (OR=0.812, 95%CI=0.720-0.914), platelet count (OR=0.993, 95%CI=0.989-0.996), and oxygen saturation level (OR=0.950, 95%CI=0.967-0.932) at the time of admission.
Conclusion: Older age, white blood cell count, hemoglobin level, oxygen saturation level, and platelet count are predictors of death among older inpatients with COVID-19. Identification of these risk factors can assist the healthcare providers for timely intervention for the prevention of death.
Article number: 2
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Type of Study: Research | Subject: Infectious Disease

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