Volume 25, Issue 3 (In Press_ Autumn 2021)                   2021, 25(3): 0-0 | Back to browse issues page

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Madani P S, Mirzadeh M, Rosamain S. The difference between IgG level in outpatients and in patients with COVID-19 in Qazvin. Journal of Inflammatory Diseases. 2021; 25 (3)
URL: http://journal.qums.ac.ir/article-1-3259-en.html
1- Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran , drparisamadani@gmail.com
2- Metabolic Diseases Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran
Abstract:   (325 Views)
Background: Coronavirus disease (COVID-19) has rapidly become a pandemic since it was first recorded in December 2019. Serological reports are of great value to medical specialists in organizing health policies.
Objective: The detection of COVID-19 IgG levels can specify a preclinical infection or previous exposure to the virus.
Methods: This is a cross-sectional study carried out on patients with confirmed COVID-19 using the PCR test in Qazvin in 2020. The total sample size of the study was 172 patients, including 86 inpatients and 86 outpatients. In order to indicate IgG levels, the serum samples were collected among positive cases for COVID-19, after 3-5 weeks of their clinical symptoms. Data were statistically analyzed using the statistical package for social sciences version 20 (SPSS-20) at the level of p<0.05.
Findings: Among 172 patients, 81 (94.2%) inpatients and 74 (86%) outpatients were IgG positive cases, while 5 (5.8%) inpatients and 10 (11.6%) outpatients were negative cases for the IgG. The mean IgG level in the inpatient group was significantly higher than in the outpatient group (P value < 0.001) in the period of 3 to 5 weeks after a positive PCR test.
Conclusion: The amounts of IgG in the sera of COVID-19 patients 3-5 weeks after observation of the manifestations can improve policies and plans for control strategies by indicating the burden of disease, monitoring the spread of infection, and estimating epidemiological variables.
Article number: 8
     
Type of Study: Short communication | Subject: Infectious Disease

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