Volume 7, Issue 5 (winter 2004)                   J Qazvin Univ Med Sci 2004, 7(5): 25-29 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ayazi P, Daneshi M. Comparison of blood cultures and endotoxin measurements in diagnosis of gram negative bacterial infections. J Qazvin Univ Med Sci. 2004; 7 (5) :25-29
URL: http://journal.qums.ac.ir/article-1-399-en.html
Abstract:   (12103 Views)
Background: Gram negative bacterial infections continue to cause mortality due to unavailability of new methods for rapid diagnosis and appropriate treatment. Objective: To evaluate and compare blood culture results with endotoxin measurements in diagnosis of gram negative bacterial infections. Methods: This research was conducted on 100 hospitalized patients with clinical signs and symptoms compatible with septicemia. Blood cultures and endotoxin measurements (limulus amebocyte lysate, LAL test) were carried out on blood samples of all patients. Findings: Blood cultures were positive in 16(16%) patients. Sensitivity and specificity of blood cultures were 18% and 100%, respectively. LAL tests were positive in 20(20%) patients. Sensitivity and specificity of LAL test were 100% and 96% respectively. Conclusion: LAL test as a diagnostic assay for gram negative bacterial infections is more sensitive than blood culture. In addition, it takes only a few minutes to be performed, comparing blood culture that takes days.
Full-Text [PDF 165 kb]   (5220 Downloads)    
Type of Study: Research | Subject: Clinical Laboratory

Add your comments about this article : Your username or Email:

© 2020 All Rights Reserved | The Journal of Qazvin University of Medical Sciences

Designed & Developed by : Yektaweb