Volume 12, Issue 2 (Summer 2008)                   J Qazvin Univ Med Sci 2008, 12(2): 13-19 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jalilolghadr S, Kashanipoor N, Javadi M. The effect of zinc supplementation on linear growth in short stature school-aged children in Qazvin. J Qazvin Univ Med Sci. 2008; 12 (2) :13-19
URL: http://journal.qums.ac.ir/article-1-380-en.html
, Email: shabnam _ jalilolgadr@yahoo.com
Abstract:   (8883 Views)
Abstract Background: Physical growth retardation is an early and prominent feature of zinc deficiency. Objective: To determine the effect of zinc supplementation on linear growth of school children with short stature in Qazvin during 2004-2005. Methods: The study was designed as a double-blind randomized clinical trial during a 5-month period. Anthropometric data were collected at 0, 1, 2, 3, 4, and 5 months. Measurements included plasma zinc concentration, height, weight, nutrition state. Subjects were 30 short stature female students (<3rd percentile) aged 10-11 years. Children were randomly divided into two groups, one with zinc supplementation (15mg/day ZnSo4) and the other with placebo. As control group, 15 healthy children with normal growth were included. Findings: The prevalence of short stature in children was 7.1% (52 from 725 children). The mean age was 10.5±0.5 years. After supplementation, zinc group showed a higher serum zinc concentration (89.5±12.99 vs. 81.1±9.04 µg/dl, p=0.009) compared to the placebo group (72.66±7.82 vs. 86.13±17.8 µg/dl) with one child found to have serum zinc concentration of less than 70 µg/dl. The linear growth rose at 3, 4, and 5 months following supplementation. The height velocity was significantly increased in zinc group (3.22±0.9cm) comparing with placebo (2.33±0.7cm) and control (3.02 ±1.59cm) groups (p=0.004). The weight increase was statistically significant only at the end of 5 months compared to the beginning of study. Conclusion: Zinc supplementation caused an increase in growth velocity and serum zinc concentration. Regarding the notable prevalence of zinc deficiency in female students during the adolescence growth spurt, zinc supplementation is recommended.
Full-Text [PDF 160 kb]   (2784 Downloads)    
Type of Study: Research | Subject: Pediatrics

Add your comments about this article : Your username or Email:
CAPTCHA code

Send email to the article author


© 2018 All Rights Reserved | The Journal of Qazvin University of Medical Sciences

Designed & Developed by : Yektaweb