[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Search :: Archive :: Registration :: Submit :: Site Map :: Contact ::
:: Volume 21, Issue 2 (Jun _ Jul 2017) ::
J Qazvin Univ Med Sci 2017, 21(2): 94-79 Back to browse issues page
Bacteriocins: New generation of antimicrobial peptides
P. Motahari , Z. Amini-Bayat , S. Mirdamadi *
Department of Biotechnology, Iranian Research Organization for Science & Technology (IROST), Tehran, Iran , mirdamadi@irost.ir
Abstract:   (1953 Views)

     Antibiotics are used as a first-choice to inhibit microbial growth since the discovery in the first half of the 19th century. Nevertheless, the widespread use of antibiotics has resulted in the emergence of antibiotic-resistant strains that is one of our century problems. Concerns about antibiotic resistant is so serious which huge budget is allocated for discovery of alternative drugs in many countries. Bacteriocin is one of these compounds which was first discovered in 1925, released into the medium by E. coli. Bacteriocins are antimicrobial peptides or proteins ribosomally synthesized by many bacterial species. The use of this antimicrobial molecules in food industry obviate consumers need to safe food with least interference of chemical substances. Nisin, the most well-known bacteriocin, is the first bacteriocin found its way to food industry. Despite the widespread application of bacteriocins, resistance is seen in some species. Although it’s exact mechanism is not clear. So according to the today’s world need to find effective methods to control pathogens, studies of bacteriocins as a substitute for antibiotics are so important. The present review has studied the structure and activity of five classes of bacteriocins from gene to function in gram positive bacteria.

Keywords: Bacteriocin, Antimicrobial activity, Structure, Classification
Full-Text [PDF 435 kb]   (657 Downloads)    
Type of Study: Review article | Subject: Biotechnology
Send email to the article author

Add your comments about this article
Your username or Email:

Write the security code in the box >

XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Motahari P, Amini-Bayat Z, Mirdamadi S. Bacteriocins: New generation of antimicrobial peptides. J Qazvin Univ Med Sci. 2017; 21 (2) :94-79
URL: http://journal.qums.ac.ir/article-1-2136-en.html

Volume 21, Issue 2 (Jun _ Jul 2017) Back to browse issues page
مجله علمی دانشگاه علوم پزشکی قزوین The Journal of Qazvin University of Medical Sciences
Persian site map - English site map - Created in 0.15 seconds with 32 queries by YEKTAWEB 3705