Volume 18, Issue 2 (June-July 2014)                   J Qazvin Univ Med Sci 2014, 18(2): 30-38 | Back to browse issues page

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Peymani A, Naserpour Farivar T, Ghoraiian P, Najafipour R. Association between class 1 integrons and multidrug resistance pattern among Enterobacter spp. isolated from Qazvin and Tehran teaching hospitals. J Qazvin Univ Med Sci. 2014; 18 (2) :30-38
URL: http://journal.qums.ac.ir/article-1-1557-en.html
1- Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
2- Qazvin University of Medical Sciences, Qazvin, Iran
3- , r_najafipour@yahoo.com
Abstract:   (5519 Views)

  Background: Multi-drug resistant (MDR) Enterobacter spp. containing class 1 integrons are considered as one of the major concerns of clinicians and infection control specialists .

  Objective: The aim of this study was to determine the association between class 1 integrons and the multidrug resistance pattern among Enterobacter spp .

  Methods: In this analytical study, antimicrobial susceptibility pattern were determined among 137 isolates of Enterobacter from Qazvin and Tehran hospitals during May 2011-September 2012. Then all isolates were screened for class 1 integrons using PCR assay. Data were analyzed using chi-square test and Fisher's exact test.

  Findings: The MDR pattern was found in 83 isolates (61%) and class 1 integrons were detected in 52 (63%) of these isolates. There was a significant association between the presence of class 1 integrons and the MDR pattern.

  Conclusion: With regards to the results, use of proper equipment for infection control and appropriate treatment strategies are necessary .





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Type of Study: Research | Subject: Microbiology

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