Volume 15, Issue 4 ( Winter 2012)                   J Qazvin Univ Med Sci 2012, 15(4): 13-19 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hosseini-Jahromi S, Hosseini-Valami S, Abdollahpour A. Comparing the effect of propofol-alfentanil with ketamine-alfentanil on endotracheal intubation without muscle relaxation. J Qazvin Univ Med Sci. 2012; 15 (4) :13-19
URL: http://journal.qums.ac.ir/article-1-1199-en.html
1- Qazvin University of Medical Sciences, Qazvin, Iran
2- Qazvin University of Medical Sciences, Qazvin, Iran , Email: parspaya872008@yahoo.com
Abstract:   (23436 Views)
Background: Endotracheal intubation is an essential and important procedure. However, in some conditions such as the presence of difficult intubation, there are some limitations for endotracheal intubation with muscle relaxation. Objective: To compare the effect of propofol-alfentanil with ketamine-alfentanil on endotracheal intubation without muscle relaxation Methods: This was a double-blind clinical trial carried out on 60 patients aged between 18-50 years old. The patients were within the ASA class I-II of anesthesia chosen for elective surgery at Shahid Rajaei Hospital in Qazvin, Iran. The participants were randomly divided into 2 equal groups. For endotracheal intubation without muscle relaxation, one group received propofol-alfentanil and another group ketamine-alfentanil. Changes in hemodynamic parameters (heart rate and blood pressure) and physical findings (vocal cord position, jaw relaxation, ability of mask ventilation, and reaction to endotracheal intubation) were compared between two groups. Data were analyzed with SPSS software using statistical tests including t-test and Chi-square test. Findings: Regarding the hemodynamic parameters, there was significant difference between two groups so that in ketamine group the hemodynamic conditions were more stable than in propofol group (P<0.05). With respect to the physical findings, 93.3% of patients in propofol group were in excellent class and 6.7% in good class whereas in ketamine group 40% were in excellent class, 33.3% in good class, and 26.7% in poor class. Statistically, there was significant difference between two groups (P<0.05). Conclusion: According to our findings, it seems that the propofol-alfentanil to produce better conditions than the ketamine-alfentanil when performing endotracheal intubation without muscle relaxation.
Full-Text [PDF 258 kb]   (1619 Downloads)    
Type of Study: Research | Subject: Anesthesiology

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


© 2019 All Rights Reserved | The Journal of Qazvin University of Medical Sciences

Designed & Developed by : Yektaweb