Volume 21, Issue 6 (Feb - Mar 2018)                   J Qazvin Univ Med Sci 2018, 21(6): 21-14 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Kaiialha H, Karbord A, Rastak S, Mehdipor H, Yaaghobi S, Kheshti A. The effect of ketamine on shivering in patients undergoing spinal anesthesia. J Qazvin Univ Med Sci. 2018; 21 (6) :21-14
URL: http://journal.qums.ac.ir/article-1-2250-en.html
1- , karbord2003@yahoo.com
Abstract:   (2577 Views)

Background: Sever shivering is the most common adverse effect of spinal anesthesia during and after operation that causes physiologic complication. One of the drugs that could decrease operative shivering is ketamine.
Objective: The aim of this study is the effect of ketamine to reduce shivering, during spinal anesthesia.
Methods: This prospective randomized, and double-blind clinical trial was conducted on 355 patients of candida different surgeries with spinal anesthesia in Bu-Ali and Velayat Hospitals in Qazvin (2017). Patients were randomly divided into experimental (n=175) and control (n=180) groups. For the experimental and control groups, ketamine (0.2 ml/kg) or an equal volume of distilled water were administered with intravenous infusion pumps immediately after initiating spinal anesthesia, respectively. Then degree of shivering checked by anesthesiologist with visual scale during surgery.
Findings: The rate and intensity of shivering at ketamine group significantly decreased compared to the control group. Shivering during surgery was less than in men, urological surgery and age (20-40 years) in both groups.
Conclusion: Adding ketamine to drug’s pump in patients undergoing spinal anesthesia could be effective method to control shivering during operation.

Full-Text [PDF 170 kb]   (569 Downloads)    
Type of Study: Research | Subject: Anesthesiology

1. De White J, Sessler DI. Preoperative Shivering: physiology and pharmacology. Anesthesiology 2002; 96(2): 467-84. [DOI] [PubMed]
2. Bhatnagar S, Saxena A, Kannan TR, Punj J, Panigrahi M, Mishra S. Tramadol for post operative shiverin: a double-blind comparison with pethidine. Anesthesia Intensive Care 2001; 29(2): 149-54. [PubMed]
3. Katyal S, Tewari A. Shivering: Anesthesia considerations. J Anesthesiol Clin Pharmacol 2002; 18(4): 363-76.
4. Mathews S, Al Mulla A, Varghese PK, Radim K, Mumtaz S. Postanesthetic shivering - a new look at Tramadol. Anesthesia 2002; 57(4): 394-8. [DOI] [PubMed]
5. Sagir O, Gulhas N, Topark H, Yucel A, Begec Z, Erosy O. Control of shivering during regional anesthesia: prophylactic Ketamine and Granisetron. Acta Anesthesiol Scand 2007; 51(1): 44-9. [DOI] [PubMed]
6. Misiran K, Aziz FZ. Effectiveness of low- dose Midazolam plus Ketamine in the prevention of shivering during spinal anesthesia for emergency lower limb surgery. South Afr J Anaesth Analg 2013; 19(3): 164-70. [DOI]
7. Dal D, Kose A, Honca M, Akinci SB, Basgul E, Aypar U. Efficacy of prophylactic Ketamine in preventing postoperative shivering. Br J Anaesth 2005; 95(2): 189-92. [DOI]
8. Cattaneo CG, Frank SM, Hesel TW, El-Rahmany HK, Kim LJ, Tran KM. The accuracy and precision of body temperature monitoring methodsduring regional and general anesthesia. Anesth Analg 2000; 90(4): 938-45. [DOI] [PubMed]
9. Tsai YC, Chu KS. A comparison of tramadol, amitriptyline, and meperidine for postepidural anesthetic shivering in parturients. Anesth Analg 2001; 93(5): 1288-92. [DOI] [PubMed]
10. Gangopadhyay S, Gupta K, Acharjee S, Nayak SK, Dawn S, Piplai G. Ketamine, Tramadol and Pethidine in prophylaxis of shivering during spinal anesthesia. J Anaesth Clin Pharmacol 2010; 26(1): 59-63.
11. Kose EA, Honca M, Dal D, Akinic SB, Aypar U. Prophylactic Ketamine to prevent shivering in parturients undergoing cesarean delivery during spinal anesthesia. J Clin Anesth 2013; 25(4): 275-80. [DOI] [PubMed]
12. Pazoki SH, Norouzi A, Shademan AH. Comparison effect of different doses of Ketamine with Pethedine in reducing postoperative shivering after cesarean section. Arak Med Univ J 2009; 12(2): 9-16 [In Persian]
13. Mahoori AR, Valizade Hasanloei MA, Hassani E, Sadighi F. The effect of intravenous low dose ketamine for prevention of shivering after inguinal herniorrhaohy. Urmia Med J 2013; 24(10): 779-84. [In Persian]
14. Sellden E, Lindahl SG. Amino acid-induced thermogenesis reduces hypothermia during anaesthesia and shortens hospital stay. Anesth Analg 1999; 89(6): 1551-6. [DOI] [PubMed]
15. Kelsaka E, Baris S, Karakaya D, Sarihasan B. Comparison of Ondansetron and Meperidine for prevention of shiveringin patients undergoing spinal anesthesia. Reg Anesth Pain Med 2006; 31(1): 40-45. [DOI] [PubMed]
16. Hasannasab B, Banihasham N, Khoshbakht A, ShirKhani Z. Efficacy of prophylactic low dose ketamine in preventing shivering after general anesthesia . J Mazandran Univ Med Sci J 2013; 23(103): 89-93. [In Persian]
17. Kose EA, Dal D, Akincis SB, Saricaoglu F, Aypar U. The efficacy of Ketamine for treatment of postoperative shivering. Anesth Analg 2008; 106(1): 120-2. doi: 10.1213/01. ane.0000296458.16313.7c. [PubMed]
18. Bock M, Motsch J. Postanesthetic shivering. Hospital Pharmacy. https://link.springer.com/chapter/10.1007/978-4-431-67035-3_17by M Bock - ‎2001. 42(2). 2007; 424-29. https://doi.org/10.1007/978-4-431-67035-3_17.
19. Ahmed A, Aslam M. Prevention of shivering during lower segment cesarean section; Comparison of prophylactic use of ketamine, and ketamine plus midazolam during spinal anesthesia. Professional Med J 2013; 20(3); 409-15.
20. Yousuf B, Samad K, Ullah H, Hoda MQ. Efficacy of tramadol in preventing postoperative shivering using thiopentone or Propofol as induction agent: A randomized contolled trial. J Anesthesiol Clin Pharmacol 2013; 29(4): 521-5. doi: 10.4103/0970-9185. 119166. [PubMed]
21. Nakasuji M1, Nakamura M, Imanaka N, Tanaka M, Nomura M, Suh SH. Intraoperative small dose of ketamine prevents Remifentanil-induced post anesthesia shivering. Anesth Analg 2011; 113(3): 484-7. doi: 10.1213/ANE. 0b013e318224ac4e. [PubMed]
22. Koeshardiandi M, Margarita N. The effectiveness of ketamine dose 0.25 mg/kg body weight intravenous as a therapy of shivering during spinal anesthesia in section caesaria surgery. Media J Emergency 2011. 1(1): 12.

Add your comments about this article : Your username or Email:

Send email to the article author

© 2020 All Rights Reserved | The Journal of Qazvin University of Medical Sciences

Designed & Developed by : Yektaweb