Volume 18, Issue 4 ( Oct-Nov 2014)                   J Qazvin Univ Med Sci 2014, 18(4): 9-14 | Back to browse issues page

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Esmailee M, Bigdeli M, Rahnama M. Effects of dietary supplementation with virgin sesame oil on lipid profile in rats. J Qazvin Univ Med Sci. 2014; 18 (4) :9-14
URL: http://journal.qums.ac.ir/article-1-1507-en.html
1- , Email:Mahnaz_esmailee@yahoo.com
Abstract:   (3534 Views)

  Background: Because of the relationship between sesame oil consumption and reduced cardiovascular morbidity and mortality rate, research on dietary intake of sesame oil is necessary.

  Objective: The aim of this study was to determine the effects of dietary supplementation with virgin sesame oil (VSO) on lipid profile in rats.

  Methods: This experimental study was conducted in 28 adult male rats weighing 240-350 g. The experimental groups were fed with a diet supplemented with 0.25, 0.5 and 0.75 ml/kg/day VSO via gastric gavage for 30 days and the control group received saline. Serum levels of cholesterol, triglycerides, HDL and L DL were measured. Data were analyzed using one way ANOVA with LSD as post-hoc test.

  Findings: Serum cholesterol, triglycerides and LDL levels were significantly decreased in the experimental groups compared to the control group. HDL was increased in a dose dependent fashion, but the difference was statistically significant for the 0.5 and 0.75 ml/Kg/day groups compared to the control group.

  Conclusions: With regards to the results, virgin sesame oil supplementation decreased serum lipids that is probably due to the effects of antioxidants and unsaturated fatty acids .



Keywords: Sesame Oil, Rats, Lipids
Full-Text [PDF 168 kb]   (1073 Downloads)    
Type of Study: Research | Subject: Physiology
Received: 2013/04/20 | Accepted: 2014/05/20 | Published: 2014/05/20

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